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Track record: Diabetes Mellitus (DM) triggers an excessive reaction of absolutely free-radicals. It will increase reactive oxygen species and cuts down antioxidants position and also the β cell harm. Very clear kefir was utilized for DM therapies, nevertheless it confined biomolecular exploration of its bioactive roles. Investigation aimed to analyze the results of clear kefir on the biomolecular mother nature on the glycemic status of T2DM in Bandung. Procedures: The randomized pretest-posttest Manage team was conducted by 106 T2DM clients. Study was finished in many hospitals in Bandung and Cimahi, West Java from 2012–2013. Samples were divided randomly into 3 teams: (1) T2DM with HbA1c < seven was fed a normal diet, supplemented with two hundred ml/day of very clear kefir, (two) T2DM with HbA1c > seven fed common diet and supplemented 200 ml/working day by crystal clear kefir, (3) T2DM with HbA1c was fed a normal diet program for a Handle team.